Mayo Muir

Muir–Torre syndrome Muir–Torre syndrome Medical condition Muir–Torre syndrome is a rare hereditary, autosomal dominant cancer syndrome[1]: 663 that is thought to be a subtype of HNPCC (Lynch syndrome). Individuals are prone to develop cancers of the colon, genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumors. The genes affected are MLH1,[2] MSH2,[3] and more recently, MSH6,[4] and are involved in DNA mismatch repair. Quick facts Other names, Specialty ... Muir–Torre syndrome Other names MTS Micrograph of a sebaceous adenoma, as may be seen in Muir–Torre syndrome. H&E stain. Specialty Oncology, dermatology, medical genetics Close Symptoms Muir–Torre syndrome is characterized by both:[5] At least a single sebaceous gland tumor (either an adenoma, an epithelioma, or a carcinoma) A minimum…

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